OUR Best Sellers
Revitalize Your Skin with Total Derma Care
Centellian 24 Madeca Cream Time Reverse
From Centellian 24, Dongkook Pharmaceutical’s flagship derma-cosmetic brand. Built on over five decades of expertise in Centella Asiatica, each formula harnesses the power of this skin-soothing botanical to help revive and nourish the look of skin—supporting all-day and all-night comfort, protection, and vitality.
Advanced Total Anti-Aging Care with 10 Powerful Benefits
Designed to address visible signs of skin aging, Madeca Cream Time Reverse delivers total care in one advanced formula. This multi-benefit anti-aging cream helps improve the look of elasticity, wrinkles, skin texture, and radiance while providing deep moisturizing and soothing comfort. With continued use, skin appears smoother, firmer, more refined, and revitalized—supporting a healthier, more youthful-looking complexion day and night.
Dongkook Pharmaceutical
Since 1968, Dongkook Pharmaceutical’s Madeca Skin Science
Dongkook Pharmaceutical’s cosmeceutical brand, Centellian24, leads the way in active anti-aging solutions with its key ingredient, TECA (Titrated Extract of Centella Asiatica). This innovative formula is backed by over 50 years of dermatological research from Dongkook Pharmaceutical.
TECA represents the pinnacle of our skincare innovation. It is a highly purified extract derived from Centella asiatica and contains madecassic acid, asiaticoside, and asiatic acid. TECA has been extensively studied for its skin-repair benefits and is clinically proven to help neutralize free radicals while stimulating collagen production—an essential building block for healthy-looking skin.
The Era of TECA
Titrated Extract of Centella Asiatica
TECA is an exclusive functional ingredient developed by Dongkook Pharmaceutical.
TECA is proven to be extra soothing and revitalizing, unlike regular cica.
The Making of TECA: A 180-Day Journey
Harvesting from Nature
Centella asiatica, grown wild in Madagascar, is carefully harvested and naturally dried in the ocean breeze.
Rigorous Quality Control
The raw material undergoes more than 200 meticulous quality checks to ensure safety and consistency.
High-Purity Extraction
A sophisticated 7-step extraction process is applied to achieve the highest purity of active compounds.
Experience the Full Potentialof TECA
MADECA CREAM TIME REVERSE
Boosts moisture and skin elasticity for up to 240 hours
Protein-rich formula absorbs 251%* faster into the skin
Helps enhance skin firmness and improve visible signs of anti-aging
80M SOLD
1 Tube Sold Per 3 Sec Elastic Radiance Facial Cream
*Based on cumulative sales of Centellian24 Madeca Cream from 2015 to 2025
Powered by NEW Activated TECA™
At the core of this formula is NEW Activated TECA™, Dongkook Pharmaceutical’s proprietary skin science innovation. Through a meticulous 7-step extraction process, only 2% of TECA™ is obtained from 100 kg of Centella Asiatica, ensuring exceptional purity and concentration.
This advanced ingredient delivers 3X stronger core efficacy and is enhanced with 3-layer liposomal technology, allowing active components to absorb more efficiently. With intensive, multi-depth absorption, Activated TECA™ helps support visible skin recovery, resilience, and anti-aging performance at deeper levels of the skin.
About Our Products
Why does my skin feel itchy after application?
Why does my skin feel itchy after application?
This may be part of the skin’s naturalpurging processas it adjusts to a new product. We recommend using it every 2–3 days at first, then gradually increasing frequency to allow your skin time to adapt.
Why does the texture feel heavy or sticky?
Why does the texture feel heavy or sticky?
Our product may feel rich at first, but it absorbs deeply into the skin. Adjust the amount based on your skin’s needs—apply a pea-sized amount in the morning as a nutrition cream, and use a slightly thicker layer at night as a sleeping pack.
Why does the sheet mask dry out and fall off?
Why does the sheet mask dry out and fall off?
Sheet masks are designed for 10–20 minutes of use. As the essence absorbs, the mask naturally begins to dry, which is a sign that your skin has received its concentrated dose of nutrients.
Why is the cream slightly yellowish in color?
Why is the cream slightly yellowish in color?
We do not use artificial colorants. The cream’s natural white or yellowish hue comes directly from the extracted ingredients.
Can I use this if I have acne-prone skin?
Can I use this if I have acne-prone skin?
Our Revitalizing Cream and Serum are designed to deliver moisture and nourishment, not specifically to treat acne. However, the key ingredient TECA has been scientifically shown to help soothe and rejuvenate skin, which may support overall skin health.
Are the products safe to use during pregnancy?
Are the products safe to use during pregnancy?
All products are hypoallergenic-tested and suitable for general use. However, since pregnancy can cause hormonal changes and heightened skin sensitivity, we recommend consulting your doctor before use.


